Job Description

Are you looking for a collaborative analytical chemistry role that allows you to meaningfully contribute GSK’s pre-clinical oligonucleotide pipeline?  If so, this role could be an ideal opportunity to explore.

As Scientist, Oligonucleotide Analytical Chemistry, you and your team will play an important role in the analysis and quality control of GSK’s preclinical oligonucleotide therapeutics pipeline. You will develop and execute advanced analytical methods for a diversity of synthetic oligonucleotide modalities to help accelerate GSK’s pipeline and platform technology ambitions.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career.  These responsibilities include some of the following:

• Take part in the buildout of GSK’s state-of-the-art analytical chemistry lab in our growing Oligonucleotide Sciences group

• Develop and deploy robust analytical methods to characterize novel synthetic oligonucleotides in low-and high-throughput settings

• Use advanced LC/MS-MS capabilities to fully characterize novel synthetic oligonucleotides and related species

• Help design and manage key data pipelines

• Collaborate internally and externally, representing Oligonucleotide Sciences Analytical Chemistry on project teams

• Support analytical investigations, including root cause analysis, in collaboration with cross-functional teams

• Participate in hiring, mentoring and training of junior team members, ensuring knowledge transfer and capability development

• May be responsible for the management of junior scientists or small team

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS with 5+ years, MS with 3+ years, of relevant experience.

• Experience with modern mass spectrometry methodology and data analysis as it pertains to oligonucleotides

• Strong background in LC/MS method development and method troubleshooting.

Preferred Qualifications :

If you have the following characteristics, it would be a plus:

• PhD with relevant experience

• 1+ years of experience managing laboratory scientists

• Experience with high-throughput LC/MS(-MS) data acquisition and analysis

• Experience with the LC/MS(-MS) analysis of small molecules and/or biologics

• Exposure to modern LC/MS(-MS) data analysis platforms as it pertains to oligonucleotides

• Exposure to other aspects of oligonucleotide drug discovery & development, including biology, bioanalysis, DMPK, delivery, etc.

• Excellent communication, presentation, and documentation skills

• Familiarity working in cross-functional matrix project teams

#LI-GSK

Please visit  GSK US Benefits Summary t o learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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